Toxic Chemical Testing Workshop ( Half Day )

GPL-TOX: Toxic Organic Chemical Profile


Because exposure to environmental pollutants in our food, air, water, and household products has been linked to many chronic diseases,  The Great Plains Laboratory, Inc. has created GPL-TOX, a toxic organic chemical profile that screens for 172 different toxic chemicals.  In this half-day workshop (afternoon), you will learn about some of the primary types of chemicals tested by GPL-TOX, how they can affect our health, and what steps can be taken to help detoxify the body.  

NOVEMBER 12, 2017

NOVEMBER 12, 2017


7:30am | Registration and Breakfast

8:10am | Overview of Genetic Testing

This section will provide an overview of the different types of genetic testing available and explain why Next-Generation Sequencing (NGS) is the superior form of genetic testing. It will also describe why GPL-SNP1000 is the best genetic test to use in integrative medicine, before reviewing six of the nine important pathways that it covers.

8:40am | Methylation: The MTHFR Pathway

The MTHFR pathway is important for folate metabolism, which is responsible for the formation of methionine, S-Adenosyl methionine (SAMe), and thymidylate monophosphate (dTMP). These compounds play critical roles in nucleotide synthesis (making more DNA for new cells), neurotransmitter synthesis (the chemicals in the brain), CoQ10 production, histamine breakdown, and numerous other processes. This section will review problems that can arise from mutations in the MTHFR gene and recommended interventions.

9:20am | Mental Health: Understanding the Risks for Developing Mental Health Disorders and Possible Interventions

Many neurological diseases can be linked to predisposition to polymorphisms in enzymes that either produce or metabolize neurotransmitters. Mutations to these genes can predispose patients to a variety of ailments including depression, schizophrenia, anxiety, and bipolar disorder. This section will review some of the primary genes relevant to mental health, as well as correlating treatment options.

10:00am | Morning Break

10:30am | Detoxification of Drugs and Environmental Toxicants

The environment that we live in today is the most toxic in history; in part because of the vast amounts of pharmaceutical drugs patients are being prescribed. It is important for our bodies to be able to eliminate these potentially toxic compounds. The enzymes that are critical to neutralize and eliminate them include the cytochrome P450s, the sulfur transferases, the glutathioine transferases, and the methyltransferases. This section will review mutations relevant to drug metabolism so that you may help prevent adverse drug reactions in your patients.

11:30pm | Oxalate Metabolism: Risks and Treatments

Oxalate and its acidic form, oxalic acid, are formed from diet, human metabolism, and from yeast/fungal overgrowth. Oxalates are known to combine with calcium to form crystals that can cause kidney stones, as well as build up in the bones, joints, blood vessels, lungs, and even the brain. This section will review the genetic risks of impaired oxalate metabolism and recommended treatments to prevent and reverse high oxalate levels.

12:15pm | The APoE Gene

Without the transporter proteins, cells are not able to attain the proper building blocks necessary for optimum functionality or dispose of toxic cellular waste. One of the most important transporter proteins is APOE, also known as “The Alzheimer’s Gene”. This section will review some of the diseases associated with mutations that result in faulty transport, including Alzheimer’s Disease.

12:15pm | Lunch

1:30pm | Non-Metal Toxic Chemicals and Their Effects on Health

A high percentage of all people are now exposed to a soup of toxic chemicals. Toxic chemical exposure has been implicated as a major factor in impaired learning ability, attention deficit, hyperactivity, pervasive developmental disorder, Alzheimer’s disease, depression, cancer, multiple sclerosis, and autism. Documentation of common chemicals in the environment that cause illnesses and their sources will be presented along with methods to prevent exposure and to remove them when exposure has already occurred.

2:45pm | Glyphosate, 2,4-D, GMO Foods, and the Microbiome

Corn, soy, and other foods have been genetically modified to be resistant to the weed-killers, glyphosate (Roundup™) and 2, 4-D (2, 4-dichlorophenoxyacetic acid). As a consequence, glyphosate and 2, 4-D are widely applied to food crops and the residues of these herbicides may remain on the plants that are ingested by humans and animals. In addition, many beneficial microorganisms are susceptible to glyphosate, leading to significant changes in the composition of the flora in the intestinal tracts of humans and other animals, with increases in pathogenic bacteria. Recent studies will be reviewed that have found significant associations between the ingestion of glyphosate and/or GMO foods and a variety of diseases including common cancers, autism, Alzheimer’s disease, multiple sclerosis, diabetes, multiple sclerosis, and many others.

3:30pm | Afternoon Break

4:00pm | Toxic Chemicals and Their Effect on Autism

Toxicants implicated in Autism Spectrum Disorders (ASD) include pesticides such as organophosphates and pyrethrins, phthalates used as plasticizers, solvents, toxic waste sites, air pollutants, pharmaceuticals such as acetaminophen, and heavy metals. In addition, a number of genetic factors related to chemical detoxification have also been associated with increased incidence of autism. A review of the scientific literature will indicate which chemicals are the leading suspects as causes of ASD as well as measures to prevent contamination of pregnant women and children and methods that can be used to detoxify individuals who have already been exposed to toxic chemicals.